Summary

A Postdoctoral Associate position is available in the laboratory of Hamed Jafar-Nejad, M.D., in the Department of Molecular & Human Genetics, Baylor College of Medicine. The laboratory uses cell culture, Drosophila and mouse genetics to identify and characterize genetic modifiers of human developmental disorders, in hopes of shedding light on disease pathophysiology and establishing new therapeutic strategies.

The Postdoctoral Associate will design and execute experiments related to Alagille syndrome and interpret the results. The Postdoctoral Associate will be responsible for summarizing the findings in the form of presentations and manuscripts. The Postdoctoral associate should have expertise in mouse models of human disease, preferably liver disease, and he/she will be responsible for the proposed experiments and will assist the PI (Dr. Jafar-Nejad) in reporting the results.

The Postdoctoral Associate will lead a newly funded NIH R01 project dissecting the SOX4/SOX9 transcriptional regulatory network that governs biliary development in Alagille syndrome and advancing the therapeutic potential of targeting this network in ALGS and other cholestatic diseases. There may also be opportunities to contribute to related ongoing projects in the lab.

This is a full-time position available immediately. To apply, please submit a cover letter (describing research experience, research interests, long-term career goals, and available start date), a CV, and contact information for three references.

Baylor College of Medicine typically follows similar to the NIH stipulated stipend guidelines for Postdoctoral Associates.

For more information:

https://www.bcm.edu/research/faculty-labs/hamed-jafar-nejad-lab

Job Duties

• Designs and conducts experiments related to preclinical studies on Alagille syndrome and will assist the PI in reporting the results.
• Summarizes the research findings.
• Performs statistical analyses to determine the significance of the observations. Works will be based on models and techniques already established in the laboratory, the postdoc will likely need to set up new techniques and potentially establish new disease models as well, depending on how the project proceeds.
• Communicates the results with collaborators via email exchange and virtual presentations.
• Participates in preparing grant applications.
• Performs other job-related duties as assigned.

Minimum Qualifications

• MD or Ph.D. in Basic Science, Health Science, or a related field.
• No experience required.

Preferred Qualifications

• Recent Ph.D. graduate or an M.D. with relevant research experience.
• Experience in mouse genetics is essential, preferably in the context of liver development and disease.
• Expertise in molecular biology, biochemistry, and/or bioinformatic analysis is desired.
• Has strong publication record and available to begin promptly.
• Be highly motivated scientist.